PAPER Altay O, Yang H, Yildirim S, Bayram C, Bolat I, Oner S, Tozlu OO, Arslan ME, Hacimuftuoglu A, Shoaie S, Zhang C, Borén J, Uhlén M, Turkez H, Mardinoglu A
SEARCH RESULTS
4455 RESULTS
PAPER Niazi SK, Magoola M
Transcytosis-Driven Treatment of Neurodegenerative Disorders by mRNA-Expressed Antibody-Transferrin Conjugates.
Biomedicines. 2024 Apr 12;12(4) PubMed: 38672205PAPER Jarek DJ, Mizerka H, Nuszkiewicz J, Szewczyk-Golec K
Evaluating p-tau217 and p-tau231 as Biomarkers for Early Diagnosis and Differentiation of Alzheimer's Disease: A Narrative Review.
Biomedicines. 2024 Apr 3;12(4) PubMed: 38672142PAPER Yarkova ES, Grigor'eva EV, Medvedev SP, Tarasevich DA, Pavlova SV, Valetdinova KR, Minina JM, Zakian SM, Malakhova AA
Detection of ER Stress in iPSC-Derived Neurons Carrying the p.N370S Mutation in the GBA1 Gene.
Biomedicines. 2024 Mar 27;12(4) PubMed: 38672099PAPER Lal U, Chikkankod AV, Longo L
A Comparative Study on Feature Extraction Techniques for the Discrimination of Frontotemporal Dementia and Alzheimer's Disease with Electroencephalography in Resting-State Adults.
Brain Sci. 2024 Mar 29;14(4) PubMed: 38671987PAPER Zhang MX, Hong H, Shi Y, Huang WY, Xia YM, Tan LL, Zhao WJ, Qiao CM, Wu J, Zhao LP, Huang SB, Jia XB, Shen YQ, Cui C
A Pilot Study on a Possible Mechanism behind Olfactory Dysfunction in Parkinson's Disease: The Association of TAAR1 Downregulation with Neuronal Loss and Inflammation along Olfactory Pathway.
Brain Sci. 2024 Mar 22;14(4) PubMed: 38671952PAPER Branigan KS, Dotta BT
Cognitive Decline: Current Intervention Strategies and Integrative Therapeutic Approaches for Alzheimer's Disease.
Brain Sci. 2024 Mar 22;14(4) PubMed: 38671950PAPER Staurenghi E, Testa G, Leoni V, Cecci R, Floro L, Giannelli S, Barone E, Perluigi M, Leonarduzzi G, Sottero B, Gamba P
Altered Brain Cholesterol Machinery in a Down Syndrome Mouse Model: A Possible Common Feature with Alzheimer's Disease.
Antioxidants (Basel). 2024 Apr 3;13(4) PubMed: 38671883PAPER Jiang D, Liu H, Li T, Zhao S, Yang K, Yao F, Zhou B, Feng H, Wang S, Shen J, Tang J, Zhang YX, Wang Y, Guo C, Tang TS
Agomirs upregulating carboxypeptidase E expression rescue hippocampal neurogenesis and memory deficits in Alzheimer's disease.
Transl Neurodegener. 2024 Apr 26;13(1):24. PubMed: 38671492PAPER Yang A, Yi X, Zhang H, Shen R, Kou X
Diosmetin derivatives as multifunctional anti-AD ligands: Design, synthesis, and biological evaluation.
Chem Biol Drug Des. 2024 Apr;103(4):e14529. PubMed: 38670598PAPER Sengupta P, Sen S, Mukhopadhyay D
The receptor tyrosine kinase IGF1R and its associated GPCRs are co-regulated by the noncoding RNA NEAT1 in Alzheimer's disease.
Gene. 2024 Apr 24;918:148503. PubMed: 38670398PAPER Cayir S, Volpi T, Toyonaga T, Gallezot JD, Yang Y, Sadabad FE, Mulnix T, Mecca AP, Fesharaki-Zadeh A, Matuskey D
Relationship between neuroimaging and cognition in frontotemporal dementia: An FDG-PET and structural MRI study.
J Neuroimaging. 2024 Apr 26; PubMed: 38676301PAPER Rodrigues ME, Bolen ML, Blackmer-Raynolds L, Schwartz N, Chang J, Tansey MG, Sampson TR
Diet-induced metabolic and immune impairments are sex-specifically modulated by soluble TNF signaling in the 5xFAD mouse model of Alzheimer's disease.
Neurobiol Dis. 2024 Apr 24;196:106511. PubMed: 38670277APP C-Terminal Fragments Stifle Calcium Flow from ER to Lysosomes
RESEARCH NEWS 2024-04-27 Research News C-terminal fragments of amyloid precursor protein have been blamed for endolysosomal dysfunction in Alzheimer’s disease. Now, scientists led by Wim Annaert at KU Leuven, Belgium, claim that’s because these fragments disrupt calcium flux. In
Jessica Young on APP C-Terminal Fragments Stifle Calcium Flow from ER to Lysosomes
COMMENT In this elegant study by Bretou et al., new mechanistic evidence is provided for APP-mediated endolysosomal dysfunction in AD. Altered lysosomal Ca2+ levels due to APP-CTF accumulation at the lysosome side of lysosome-ER contact sites appear to be the dri